From the iSeeCars Longest Lasting Cars Study

How long does a GMC Sierra 2500HD last?

Q: How long does a GMC Sierra 2500HD last?

17.2% of GMC Sierra 2500HDs reach 250,000 miles, according to the iSeeCars Longest Lasting Cars Study (September 15, 2026), against 5.4% of all vehicles.

Q: Which GMC Sierra 2500HD years have known problems?

Caboose has no widely reported defect pattern on file for the GMC Sierra 2500HD.

17.2% of GMC Sierra 2500HDs reach 250,000 miles. That is 3.2 times the 5.4% average for every vehicle on the road, which earns it a 300K Caboose mile rating.

300KMile rating

17.2%reach 250,000 miles

75%of the 67 ranked models have lower odds

$0.18cheapest remaining mile among 20 for sale today

Check yours

Model years with known problems

We have no widely reported defect pattern on file for the GMC Sierra 2500HD. Individual cars still vary, so check the VIN history and get an inspection.

Shopping for a Sierra 2500HD?

20 used Sierra 2500HDs are for sale on Caboose today, from $19,388.

See Sierra 2500HDs for sale

Ram 350031.9% reach 250,000
Toyota Tundra28.2% reach 250,000
GMC Sierra 3500HD26.2% reach 250,000

Source: iSeeCars Longest Lasting Cars Study, published September 15, 2026, more than 395 million vehicles.